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Pausing DMARDs After Booster May Increase Disease Flares

1d ago

Pausing DMARDs After Booster May Increase Disease Flares
Image: medscape.com

A large trial found that pausing DMARD therapy after a COVID booster did not improve immune response but was linked to more disease flares. Researchers advise against temporarily stopping these treatments.

Why it matters

This matters for people on DMARDs considering booster vaccines; the evidence comes from a randomized trial.

Key facts
study
Temporarily pausing DMARD therapy following a COVID booster vaccine

Taken from the source as published — check the details before acting on them.

Study design and population

The trial involved a large group of patients on DMARDs who received a COVID booster, with some pausing their medication temporarily.

Immune response findings

Pausing DMARDs did not enhance the immune response to the booster vaccine, according to the researchers.

Disease flare outcomes

Patients who paused their DMARDs experienced more disease flares compared to those who continued their treatment.

Common questions

Should people on DMARDs pause their medication after a booster?

The study suggests pausing DMARDs after a booster may increase disease flares and does not improve immune response.

What type of study was this?

This was a large randomized clinical trial examining the effects of pausing DMARDs after a COVID booster.

Sources

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